The horned lizard, also know as a 'horny toad' is the largest non-boss enemy in the game. They appear later in the game and give a considerable amount of damage. Their attacks in include headbutting and squirting blood out of their eyes They can also lower their head to block attacks from the player. They are worth 250 points. 

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The Scorpion battling a Horned Lizard

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Tarantula vs Horned Lizard